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赵姗

  • 北京大学未来技术学院国家生物医学科学成像中心研究员、博士生导师
  • 个人简介
    生物体的整体分子和结构研究旨在全面解析生物体在分子、细胞、组织和器官水平上的组成、结构、功能及其相互关系。赵姗实验室结合组织透明化、先进成像系统（例如光片）和深度学习分析等手段致力于开发三维多组学技术，系统性描绘和定量控制生物体在生理和病理变化下的复杂分子和结构关系，以广泛用于生物医学研究，包括癌症和微生物组、脑中风、定量医学等。
  • 所授课程
    《分子医学高级教程》（1堂主题课）
  • 获奖及荣誉
    国家优秀自费留学生奖学金
  • 个人履历
    2024-现在 北京大学 研究员/助理教授
    2021-2024 苏黎世大学/苏黎世联邦理工 博士后
    2017-2020 慕尼黑大学 博士
    2013-2017 北京大学 科研助理
    2010-2013 清华大学 科研助理
    2007-2009 北京理工大学 硕士
    2003-2007 北京理工大学 本科
  • 代表性论文及论著
    1.Jie Luo*; Muge Molbay*; Ying Chen*; Izabela Horvath*; Karoline Kadletz*; Benjamin Kick*; Shan Zhao*; Rami Al-Maskari; Inderjeet Singh; Mayar Ali; Harsharan Singh Bhatia; David-Paul Minde; Moritz Negwer; Luciano Hoeher; Gian Marco Calandra; Bernhard Groschup; Jinpeng Su; Ceren Kimna; Zhouyi Rong; Nikolas Galensowske; Mihail Ivilinov Todorov; Denise Jeridi; Tzu-Lun Ohn; Stefan Roth; Alba Simats; Vikramjeet Singh; Igor Khalin; Chenchen Pan; Bernardo A. Arús; Oliver T. Bruns; Reinhard Zeidler; Arthur Liesz; Ulrike Protzer; Nikolaus Plesnila; Siegfried Ussar; Farida Hellal; Johannes Paetzold; Markus Elsner; Hendrik Dietz; Ali Erturk ; Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning, Nature Biotechnology, 2025, 1-14
    2.de Souza, N., Zhao, S. & Bodenmiller, B. Multiplex protein imaging in tumour biology. Nat Rev Cancer 24, 171–191 (2024).
    3.Nikita Vladimirov*, Fabian F. Voigt*, Thomas Naert, Gabriela R. Araujo, Ruiyao Cai, Anna Maria Reuss, Shan Zhao, Patricia Schmid, Sven Hildebrand, Martina Schaettin, Dominik Groos, José María Mateos Melero, Philipp Bethge, Taiyo Yamamoto, Valentino Aerne, Alard Roebroeck, Ali Ertürk, Adriano Aguzzi, Urs Ziegler, Esther Stoeckli, Laura Baudis, Soeren S. Lienkamp, and Fritjof Helmchen. The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples. Nat. commu.,15, 2679 (2024).
    4.Doris Kaltenecker*, Rami Al-Maskari*, Moritz Negwer*, Luciano Hoeher, Florian Kofler, Shan Zhao, Mihail Todorov, Johannes Christian Paetzold, Julia Geppert, Pauline Morigny, Bjoern H. Menze, Stephan Herzig, Mauricio Berriel Diaz, Ali Ertürk. Virtual reality-empowered deep-learning analysis of brain cells. Nature Methods, (2024).
    5.Ruiyao Cai*, Zeynep Ilgin Kolabas*, Chenchen Pan, Hongcheng Mai, Shan Zhao, Doris Kaltenecker, Fabian F. Voigt, Muge Molbay, Tzu-lun Ohn, Cecile Vincke, Mihail I. Todorov, Fritjof Helmchen, Jo A. Van Ginderachter, Ali Ertürk. Whole-mouse clearing and imaging at the cellular level with level with vDISCO. Nature Protocols, 1197–1242 (2023).
    6.Hongcheng Mai*, Zhouyi Rong*, Shan Zhao*, Ruiyao Cai, Hanno Steinke, Ingo Bechmann, Ali Erturk. Scalable SHANEL Tissue Labelling and Clearing for Intact Human Organs. Nature Protocols. 2022, 1-35.
    7.Shan Zhao, Mihail Ivilinov Todorov, Ruiyao Cai, Rami AI-Maskari, Hanno Steinke, Elisabeth Kemter, Hongcheng Mai, Zhouyi Rong, Martin Warmer, Karen Stanic, Oliver Schoppe, Johannes Christian Paetzold, Benno Gesierich, Milagros N. Wong, Tobias B. Huber, Marco Duering, Oliver Thomas Bruns, Bjoern Menze, Jan Lipfert, Victor G. Puelles, Eckhard Wolf, Ingo Bechmann, Ali Ertürk. Cellular and Molecular Probing of Intact Human Organs. Cell, 2020,180,1-17.
    Ruiyao Cai*, Chenchen Pan*, Ghasemigharagoz A, Todorov MI, Forstera B, Zhao S, Bharia HS, Mrowka L, Theodorou D, Rempfle M, Xavier A, Kress BT, Benakis C, Liebscher S, Liesz A, Menze B, Kerschensteiner M, Nedergard M, Erturk A. Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections. Nature Neuroscience (cover), 2019,22,317–327.