Recently, the annual list of the top 10 social impact events in China’s optics field, known as Light10, was announced for 2023. Professor Chen Liangyi's team from the National Biomedical Imaging Center (NCBI) was recognized for their groundbreaking work,  "Quantitatively mapping local quality of super-resolution microscopy by rolling Fourier ring correlation."

Selected Achievement " Quantitatively mapping local quality of super-resolution microscopy by rolling Fourier ring correlation"

The collaborative effort between Weisong Zhao/Haoyu Li at Harbin Institute of Technology and Liangyi Chen at Peking University has proposed an autocorrelation two-step deconvolution super-resolution imaging method. This method significantly enhances the switching contrast of fluorescence dynamics by at least two orders of magnitude. Utilizing this technique, the team has achieved the highest throughput in super-resolution imaging within living cells to date. The temporal resolution is enhanced by approximately 50 times, and a more than 2-fold improvement in 3D spatial resolution is attainable using just 20 frames, without additional hardware.

Moreover, the NCBI's team, led by Prof. Cheng Heping and Prof. Wang Aimin, was nominated for the Top 10 Social Influence Events in China's Optical Sector in 2023 for their development of "Miniature Three-Photon Microscopy Maximized for Scattered Fluorescence Collection." This innovative microscopy device, weighing only 2.17g, is capable of penetrating deep brain structures such as the cerebral cortex and corpus callosum. For the first time, it allows functional imaging of the entire cerebral cortex and hippocampal neurons in freely behaving mice, offering a new paradigm for exploring neural mechanisms within deep brain structures.

Light10 is an esteemed annual compilation of the ten most influential events in China's optics industry. It is organized by Light: Science & Applications, a leading journal in China's Action Plan for Excellence in Science and Technology, in collaboration with Sciencenet, the premier science communication brand under China Science News. Since its inception in 2019, the award has been successfully held for five years, celebrating significant advancements and contributions to the field of optics.

(Source: Chinese Optics WeChat)