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ZHANG Jue

  • Associate Professor, Doctoral Advisor
  • College of Engineering, Peking University
    BioMed-X Center, Academy for Advanced Interdisciplinary Sciences, Peking University
    National Biomedical Imaging Center
  • 个人简介
    Dr. Zhang has worked closely with clinical hospitals for a long time, engaged in clinical problem-driven interdisciplinary research involving medical imaging and biomedical data processing and analysis. A series of encouraging breakthrough research achievements have been made in the fields of non-invasive quantitative perfusion and oxygen metabolism NMR imaging of arterial vascular diseases, ultrasound-resolution imaging of tiny vessels, ultrasound-labeled imaging of single vessels, functional ultrasound contrast agent design, controlled release of ultrasound-loaded drugs, and data mining and analysis based on nonlinear dynamic complex networks.
  • 所授课程
    Introduction to Biomedical Engineering (postgraduate, compulsory, 3 credits)
    Principle and Sequence Design of Magnetic Resonance Imaging (postgraduate, elective, 3 credits)
    Magnetic Resonance Imaging Experiment (postgraduate, elective, 3 credits)
    Nonlinear Signal Processing and Analysis (postgraduate, elective, 3 credits)
    Solid Mechanics, Experiment (undergraduate, compulsory, 3 credits)
    Principles of Medical Imaging (undergraduate, elective, 3 credits)
  • 个人履历
    2021-present, National Biomedical Imaging Science Center, PI, Peking University
    2019-now, Director of Brain Observatory Data Center, Nanjing Translational Research Institute, Institute of Molecular Medicine, Peking University
    2019, selected as a member of Beijing Strategic Talent Team
    2017, Vice Chairman of Testing Technology Committee of China Food and Drug Enterprise Quality and Safety Promotion Association
    2006-present, Associate Professor, Doctoral advisor, School of Engineering, Peking University
    2006-present, Doctoral advisor, Academy for Advanced Interdisciplinary Sciences, Peking University
    2006-2007, Visiting Scholar, Frank Reidy Center for Bioelectricity Research, Old Dominion University, USA
    2003-2006, Lecturer, Department of Mechanics and Engineering Science, Peking University
    1993-1997 Assistant Engineer, Engineering Department, Zhuhai Electric Power Industry Bureau, Guangdong Province
    2003, Engineering Mechanics from the Department of Mechanics and Engineering Science, Peking University, Ph. D.
    2000, Experimental Mechanics from the Department of Mechanics and Engineering Science, Peking University, Master
    In 1993, Department of Architectural Engineering, China Agricultural University, Bachelor
  • 代表性论文及论著
    1. Enhanced Acoustic Droplet Vaporization through the Active Magnetic Accumulation of Drug-Loaded Magnetic Particle-Encapsulated Nanodroplets (MPE-NDs) in Cancer Therapy, Nano Letters, 2022，doi.org/10.1021/acs.nanolett.2c02580.
    2. Arterial Labeling Ultrasound Subtraction Angiography (ALUSA) Based on Acoustic Phase-change Nanodroplets, Small,2022,18 (12) 2105989.
    3. Blinking Acoustic Nanodroplets Enabling Fast Super-resolution Ultrasound Imaging, ACS Nano,2021, 15(10) 16913–16923.
    4. Ultrasound Microvascular Imaging Based on Super‐Resolution Radial Fluctuations, Ultrasound in Medicine & Biology, 2020, 8:53223-53231.
    5. Cold Plasma gas loaded microbubbles as a novel ultrasound contrast agent, Nanoscale, 2019,11,1123-1130.
    6. Flow Artifact Removal in Carotid Wall Imaging based on Black- and Gray- Blood Dual Contrast Images Subtraction, Magnetic Resonance in Medicine 2017,77(4):1612-1618.
    7. Simultaneous Dynamic R2, R2' and R2* Measurement using Periodic π Pulse Shifting Multi-echo Asymmetric Spin Echo (psMASE) Sequence and Moving Estimation Strategy: A Feasibility Study for Lower Extremity Muscle, Magnetic Resonance in Medicine, 2017,77(2):766–773.
    8. Turbo fast three‐dimensional carotid artery black‐blood MRI by combining three‐dimensional MERGE sequence with compressed sensing, Magnetic Resonance in Medicine, 2013,70(5):1347-1352.
    9. Quantitative cerebral blood flow (CBF) mapping and Functional Connectivity of Postherpetic Neuralgia Pain (PHN): A Perfusion fMRI study, Pain, 2013,154:110–118.
    10. Intranasal Insulin Enhanced Resting-State Functional Connectivity of Hippocampal Regions of in Type 2 Diabetes, Diabetes, 2015,64(3): 1025-1034.
    11. Apparent Diffusion Coefficients of Metabolites in patients with MELAS Using Diffusion Weighted Magnetic Resonance Spectroscopy, American Journal of Neuroradiology, 2012,32(5): 898-902.
    12. Quantitative Assessment of External Carotid Artery Territory Supply with Modified Vessel Encoded Arterial Spin Labeling, American Journal of Neuroradiology, 2012,33(7):1380-1386.
    13. Direct current stimulation over the human sensorimotor cortex modulates the brain's hemodynamic response to tactile stimulation, European Journal of Neuroscience, 2015,42(3): 1933-1940.
    14. Quantitative Coordination Evaluation for Duchenne Muscular Dystrophy Children, Chaos, 2020, 30(2):023116.
    15. Encoding of Social Novelty by Sparse GABAergic Neural Ensembles in the Prelimbic Cortex, Science Advances, 2022 DOI: 10.1126/sciadv.abo4884.
    16. Su-MICL: Severity-Guided Multiple Instance Curriculum Learning for Histopathology Image Interpretable Classification, IEEE Transactions on Medical Imaging, 2022，doi: 10.1109/TMI.2022.3188326.