中文
Faculty
  • 办公地址:

    222, Wangkezhen Building, Peking University

  • 电子邮箱:

    sun_yujie@pku.edu.cn

SUN Yujie

  • Professor, Doctoral Advisor
  • Vice President, College of Future Technology
    Boya Distinguished Professor, National Biomedical Imaging Center
    Biomedical Pioneering Innovation Center
    National Key Laboratory of Membrane Biology
    National major science and technology infrastructure of multi-mode and cross-scale biomedical imaging, vice-chief engineer
  • 所授课程
    Physics in Cells (elective, 3 credits)
  • 获奖及荣誉
    Overseas High-Level Talents Youth Program (2011)
    SCOPUS Young Researcher Award in Life Sciences(2012)


    重点词汇
    158/5000
    翻译
    通用场景
    Tonghua Dongbao Life Science Scholarship (2014)
    Outstanding Doctoral Dissertation Supervisor of Peking University (2015)
    Outstanding Head Teacher Model of Peking University (2016)
    Bayer Investigator Award (2017)
    Winner of Outstanding Youth Fund of National Foundation of China (2019)
    Boya Distinguished Professor, Peking University (2019)
    Peking University Fangzheng Teacher Award (2019)
    Excellent Doctoral Thesis Advisor of Peking University (2022)
  • 教育背景
    1999-2005, University of Pittsburgh Department of Chemistry, USA, Tutor: Gilbert C. Walker, PhD
    1996-1999, Department of Chemistry, University of Science and Technology of China, Tutor: Zheng Nengwu, Master
    1992-1996, Department of Applied Chemistry, University of Science and Technology of China
  • 工作简历
    2020.08 -- Present, Tenure Professor, Biomedical Frontier Innovation Center (BIOPIC), Peking University
    2019.02-2020.07, Biomedical Frontier Innovation Center (BIOPIC), Peking University, Associate Tenure Professor
    2011.01-present: Researcher, Biodynamic Optical Imaging Center (BIOPIC), Peking University
    2005-2010, Muscle Institute & Nano/Bio Interface Center, University of Pennsylvania, Instructor: Yale E. Goldman, Postdoctoral Researcher

    Journal services:
    Editorial board member of Chinese Chemical Letter
    Editorial member of the PhotoniX Journal
    Editorial Board, Journal of Chemical & Biomedical Imaging
    Editor of Advances in Laser and Optoelectronics
    Academic services:
    Member, Biophysical Chemistry Committee, Chinese Chemical Society
    Deputy Director of confocal Professional Committee of Chinese Electron Microscopy Society
    Member, Professional Committee of single Molecule Biology, Chinese Biophysical Society
    Member, Organelle Biology Branch, Chinese Society for Cell Biology
    Vice President of Microscopic Instrument Branch of China Instrument and Meter Society
    Member, International Affairs Committee, American Society for Cell Biology
    Vice President, Molecular Imaging Branch, Chinese Cognitive Science Society
  • 承担项目
    Overseas High-level Talent Youth Program, 2012/01-2014/12, 3 million yuan, Completed, Principal Investigator
    High resolution dynamic spatial network and function of Escherichia coli MreB cytoskeleton and its binding protein, 2013/01-2016/12, 800,000 Yuan, Completed, Principal Investigator
    Major Instrument Project of the National Natural Science Foundation of China, 31327901, Ultra-high spatio-temporal Resolution Miniaturized Two-photon in Vivo microscopic imaging System, 2014/01-2018/12, RMB 72 million, in progress, participating
    National High Technology Research and Development Program (863 Program), Ministry of Science and Technology, 2015AA020406, Single-cell real-time dynamic 3D imaging new technology and device Research, 2015/01-2017/12, 10.56 million yuan, research in progress, Principal Investigator
    Project of National Natural Science Foundation of China, 21573013, Study on Fluorescent labeling of Chromatin DNA in Living Cells based on TALE and CRISPR, 2016/01-2019/12, 700,000 Yuan (direct funding), in progress, Principal Investigator
    National Key Research and Development Program, 2017YFA0505302, Protein Machine and Life Process Regulation: Dynamic Imaging of Ultra-high spatial and temporal Resolution Protein Machine, 2017/07-2022/06, 30 million yuan (direct funding), in progress, Participating
    Development of fluorescence imaging technology to study chromatin structure and function 2182541, 2019/1-2020/123.5 million yuan, Research in progress, Principal investigator
    Major scientific research instrument development Project of National Foundation of China, Subcellular Fine Structure Phenotype high-throughput super resolution screening System, 22127804, 202/1-2026/12,7115,600 yuan, in progress, Principal Investigator
  • 代表性论文及论著
    1. Wang, Sheng#; Ding, Miao#; Xue, Boxin; Hou, Yingping; Sun, Yujie*, Live Cell Visualization of Multiple Protein-Protein Interactions with BiFC Rainbow, ACS Chem. Biol., Article ASAP DOI: 10.1021/acschembio.7b00931(# equal contribution).
    2. Xuanze Chen#, Rongqin Li#, Zhihe Liu#, Kai Sun, Zezhou Sun, Danni Chen, Gaixia Xu, Peng Xi, Changfeng Wu*, & Yujie Sun*, Photoblinking small semiconductor polymer dots for fluorescence nanoscopy, Adv. Mater. 2017, 29(5),1604850. (VIP paper & cover story) (# equal contribution,*co-corresponding).
    3. Sheng Wang#, Xuanze Chen#, Lei Chang#, Ruiying Xue, Haifeng Duan, and Yujie Sun*, GMars-Q Enables Long-Term Live-Cell Parallelized Reversible Saturable Optical Fluorescence Transitions Nanoscopy, ACS Nano 2016, 10, 9136–9144 (cover story)(# equal contribution).
    4. Wanqing Du#, Qian Peter Su#, Yang Chen, Yueyao Zhu, Dong Jiang, Yueguang Rong, Senyan Zhang, Yixiao Zhang, He Ren, Chuanmao Zhang, Xinquan Wang, Ning Gao, Yanfeng Wang, Lingfei Sun, Yujie Sun* and Li Yu*, Kinesin 1 Drives Autolysosome Tubulation, Dev. Cell 2016, 37, 326–336 (#equal contribution, *co-corresponding).
    5. X.-Z. Chen, M. Wei, M.-M. Zheng, J.-X. Zhao, H.-W. Hao, L. Chang, P. Xi, and Y.-J. Sun*, Study of RNA Polymerase II Clustering inside Live-Cell Nuclei Using Bayesian Nanoscopy, ACS Nano, 2016, 10, 2447–54.
    6. S.-P. Shao, W.-W. Zhang, H. Hu, B.-X. Xue, J.-S. Qin, C.-Y. Sun, Y.-A. Sun, W.-S. Wei, Y.-J. Sun*, Long-term Dual-color Tracking of Genomic Loci by Modified sgRNAs of the CRISPR/Cas9 System, Nucleic Acids Res., 2016, 44, e86.
    7. Z. Liu, D. Xing, Q. Su, X.-Y. Kong, J.-M. Zhang, B.-X. Xue, H. Sun, S. Wang, Y.-L. Tao, Y.-J. Sun*, Super-resolution Imaging and Tracking of Protein-Protein Interaction in Subdiffraction Cellular Space, Nature Comm., 2014, 5, 4443-4449.
    8. W-.J. Zong, J. Zhao, X.-Y. Chen, Y. Lin, H.-X. Ren, Y.-F. Zhang, M. Fan, Z. Zhou, H.-P. Cheng, Y.-J. Sun* and L.-Y. Chen*, Large-field high-resolution two-photon digital scanned light-sheet microscopy, Cell Res., 2014, 5, 1-4 (*co-corresponding).
    9. S. Kim, E. Broströmer, D. Xing, J.-S. Jin, S.-S. Chong, H. Ge, S.-Y. Wang, C. Gu, L.-J. Yang, Y.-Q. Gao, X.-D. Su*, Y.-J. Sun*, X.-S. Xie*, Probing Allostery Through DNA, Science, 2013, 339, 816-819 (*co-corresponding).
    10. Y.-J. Sun, O. Sato, F. Ruhnow, M.-E. Arsenault, M. Ikebe, Y.-E. Goldman, Single Molecule Stepping and Structural Dynamics of Myosin X, Nature Struct. Mol. Biol. 2010, 17, 485-491.